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Detection of day blood filarial antigens by Og4C3 ELISA test using filter paper samples.

Identifieur interne : 012E04 ( Main/Exploration ); précédent : 012E03; suivant : 012E05

Detection of day blood filarial antigens by Og4C3 ELISA test using filter paper samples.

Auteurs : S L Hoti [Inde] ; A. Elango ; K. Radjame ; J. Yuvaraj ; S P Pani

Source :

RBID : pubmed:12502137

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English descriptors

Abstract

The launching of the global filariasis elimination programme has necessitated the use of highly sensitive and specific diagnostic tests. The Og4C3 monoclonal antibody-based ELISA test has been found to be highly specific and sensitive for the diagnosis of filariasis using night blood samples. However, it requires a serum sample which poses problems of transport and storage. Collection of blood samples on filter paper the will greatly circumvent these problems. Therefore, we evaluated the utility of the Og4C3 assay on filter paper samples collected during daytime.

PubMed: 12502137


Affiliations:


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<div type="abstract" xml:lang="en">The launching of the global filariasis elimination programme has necessitated the use of highly sensitive and specific diagnostic tests. The Og4C3 monoclonal antibody-based ELISA test has been found to be highly specific and sensitive for the diagnosis of filariasis using night blood samples. However, it requires a serum sample which poses problems of transport and storage. Collection of blood samples on filter paper the will greatly circumvent these problems. Therefore, we evaluated the utility of the Og4C3 assay on filter paper samples collected during daytime.</div>
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